Table 3. Effects of treatment on BBMEC protein expression.
Treatment Group | Actin, % | Claudin-1, % | Occludin, % | ZO-1, % | ZO-2, % |
---|---|---|---|---|---|
Normoxic | 100 ± 2 | 100 ± 1 | 100 ±2 | 100 ± 3 | 100 ± 1 |
Hypoxic | 141±11* | 99 ±5 | 97 ±5 | 102 ±4 | 97 ±6 |
Posthypoxic reoxygenation | 232 ±16† | 103 ±5 | 138 ±11† | 171±16† | 178±22† |
Data are percentage of control with means ± SE. ZO, zona occludens.
P < 0.05 and
P < 0.01 compared with normoxic conditions using one-way ANOVA and Newman-Keuls post hoc analysis.