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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Cancer Res. 2013 Oct 21;73(23):7122–7133. doi: 10.1158/0008-5472.CAN-13-1766

Table 2.

Altered Sequence of Ptch1 cDNA in medulloblastomas

Tumor ID Ptch1 mutations Altered sequences (parenthesized sequences are the deleted segments in tumor, underlined sequences are the duplicated segments)
MB20 14nt duplication in exon 10 CTGGCTGGCGTCCTGTTGGTTGCGTCCTGTTGGTTGCGCTGTCAGTGG
MB36 14nt deletion in exon 16 CAGACTGGCA(GCCGAGACAAGCCC)ATCGACATTA
MB59 4nt deletion in exon 10 GTCCTGTTGG (TTGC) GCTGTCAGTG
MB73 14nt duplication in exon 10 CTGGCTGGCGTCCTGTTGGTTGCGTCCTGTTGGTTGCGCTGTCAGTGG
MB79 7nt deletion in exon 18 CCTACGAGAC(ACCTCAG)ACTTTGTGGA
MB89 Deletion: 3nt of exon 11, Intron-11, and 123nt of exon 12. ATTCCATTTG(AGG-Intron 11-ACAGGACTGGGGAGTGCCTCAAGCGCACCGGAGCCAGCGTGGCCCTCACCTCCATCAGCAATGTCACCGCCTTCTTCATGGCCGCATTGATCCCTATCCCTGCCCTGCGAGCGTTCTCCCTCC)AGGCTGCTGT