Table 3.
Half-Life of Molecular and DNA-Au NP Systems for More Salt Inhibited (Wild-Type) and More Salt Tolerant (Turbo) Nucleases
| wild-type DNase I (more salt dependent) |
turbo DNase (less salt dependent) |
|||
|---|---|---|---|---|
| system | half-life (minutes) |
relative increasea |
half-life (minutes) |
relative increasea |
| Molecular DNA | 23 ± 4 | 1 | 32 ± 1 | 1 |
| DNA-Au NP | 100 ± 16 | 4.3 | 48 ± 2 | 1.5 |
| PEG 1 | 97 ± 11 | 4.2 | 48 ± 3 | 1.5 |
| PEG 2 | 67 ± 12 | 2.9 | 44 ± 5 | 1.4 |
| PEG 3 | 48 ± 4 | 2.1 | 38 ± 3 | 1.2 |
a
The relative increase in half-life normalized to molecular DNA.