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. Author manuscript; available in PMC: 2014 Feb 9.
Published in final edited form as: Br J Haematol. 2010 Nov 18;152(1):99–107. doi: 10.1111/j.1365-2141.2010.08432.x

Fig 1.

Fig 1

FVIIa clot activity and clot formation during in vivo elimination of NN1731 or rFVIIa in haemophilia A dogs. A bolus of 0·28 mg/kg NN1731 (squares) or rFVIIa (circles) was administered i.v. to haemophilia A dogs. (A) FVIIa clotting activities (closed symbols) measured according to standard procedures using a rFVIIa calibrator for analysis of both NN1731 and rFVIIa samples. (B) Clot propagation (α-angle) (open symbols) measured by thrombelastographic profiling. Data are means ± SD (n = 2).