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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Aliment Pharmacol Ther. 2013 Nov 17;39(2):163–175. doi: 10.1111/apt.12555

TABLE 1.

Patient Characteristics

Weight-based dose (n=25) Individualized dose (n=25) P
Male 10 (40%) 12 (48%) 0.78
Mean age (years) 36.5±16.1 34.1±13.1 0.57
Mean weight (kg) 70.1±20.5 73.2±19.8 0.59
White 24 (96%) 23 (92%) 1.0
Adults/children 22/3 23/2 1.0
Disease duration (months) 70±114 114±127 0.20
Disease location 0.68
 Ileal 9 (36%) 11 (44%)
 Colonic 4 (16%) 2 (8%)
 Ileocolic 12 (48%) 12 (48%)
Steroid status 0.49
 Steroid-dependent 12 (48%) 12 (48%)
 Steroid-refractory 9 (36%) 6 (24%)
 Steroid-naive 4 (16%) 7 (28%)
Baseline TPMT (EU/mL RBC) 28.9±7.6 28.6±9.2 0.90
High/Intermediate TPMT 21/4 19/6 0.73
Current smoking 2 (8%) 3 (12%) 1.0