. Author manuscript; available in PMC: 2014 Feb 9.

Published in final edited form as: Mol Reprod Dev. 2011 Jan;78(1):33–47. doi: 10.1002/mrd.21264

TABLE I.

Fer siRNA Inhibition Meiotic Maturation in a Dose-Dependent Manner

Treatment	Concentration (mM)	n	1hr GV	3 hr GV	17 hr GV	MI-MII	MII
Non-injected	0	36-41	5^b	0^c	0^a	100^a	82^a
Control siRNA	0.30	42-90	19^b	4^c	0^a	95^ab	76^a
Fer siRNA	0.05	39-50	81^a	44^b	2^a	78^b	35^b
Fer siRNA	0.10	38-45	98^a	60^ac	21^a	54^c	16^bc
Fer siRNA	0.30	44-53	100^a	93^a	54^b	31^d	2^c

Data presented as percentages of oocytes with a visible GV at 1, 3, or 17 hr of maturation or reached at least metaphase-I (MI p MII) and those that matured all the way to metaphase-II (MII) at 17 hr with 3-4 replicates per treatment. a,b,c Values in columns with different superscripts are significantly different at P < 0.05.