Skip to main content
. 2014 Feb 10;5:43. doi: 10.3389/fmicb.2014.00043

Figure 4.

Figure 4

N. marisprofundi infection induces host muscle decomposition. (A–C) Diagrams based on many TEM micrographs integrated to show body wall muscle decomposition by N. marisprofundi. C, cuticle; H, hypodermis; S, sarcomeres; MN, muscle nucleus; GT, genital tract, DE developing egg, MNC muscle non-contractile region. Microsporidia spores are represented by gray ovals. (D) A Nomarski DIC transverse section of an infected female harboring spores (arrow). (E,F) TEM micrographs of infected (E) and non-infected (F), worms. C, cuticle; MFs, muscle filaments; E, developing egg. Developing spores (arrowheads) are localized near detached muscle filaments (arrow). (G) Sporoblast (SP) and spores in a cyst-like host tissue (arrowheads) C, cuticle; E, developing egg. (H) Muscle filaments (arrow) and nucleus (arrowhead) decomposition in a severely infected host. (I) Muscle filaments (arrowheads) consumed by N. marisprofundi. Scale bars are 20 μm (D); 10 μm (A); 1 μm (B,C,H); 2 μm (E–G); 0.5 μm (I).