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Significantly mutated genes in MDS. (a) Frequency of mutations in 47 significantly mutated genes in 944 cases with different WHO subtypes, which are shown in indicated colors. (b) Frequency of gene mutations involved in common functional pathways, which are defined in Supplementary Table S3. (c) Number of gene mutations detected in different MDS subtypes. (d) Distribution of mutations/deletions of significantly mutated genes in 944 MDS cases.
