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. 2013 Nov 5;5(1):73–77. doi: 10.1021/ml4003925

Figure 2.

Figure 2

Effects of MOMIPP (1) and related 2-indolyl-substituted pyridinylpropenones on morphology of U251 glioblastoma cells. Cells were observed by phase contrast microscopy on days one and two after the addition of the indicated compounds at 10 μM. Vacuoles appear as clusters of phase-lucent puncta within the cytoplasm of the cells. Rounded cells that are poorly focused in the cultures treated with 1 and 18 have detached from the surface of the dish.