Table 1.

miRNAs expression in rat frontal cortex after saline or enoxacin treatment.

Group	Let-7a		miR-124		miR-125a-5p		miR-132		GAPDH mRNA
	Cta	Fold-change compared to shamb	Ct	Fold-change compared to sham	Ct	Fold-change compared to sham	Ct	Fold-change compared to sham	Ct	Fold-change compared to sham
Saline-treated N = 14	21.98 ± 0.52	1.00	21.53 ± 0.45	1.00	22.61 ± 0.84	1.00	20.94 ± 0.44	1.00	18.51 ± 0.39	1.00
Enoxacin (10 mg/kg) N = 12	18.39 ± 1.74	12.34	19.54 ± 1.5	4.08	19.28 ± 2.05	10.38	19.43 ± 1.06	2.92	18.55 ± 0.42	0.97
		(p = 6.9 × 10−8)		(p = 0.000038)		(p = 0.0000048)		(p = 0.000046)
Enoxacin (25 mg/kg) N = 12	17.84 ± 0.91	17.90	18.99 ± 2.68	5.93	18.1 ± 1.09	22.33	18.81 ± 0.71	4.46	18.54 ± 0.34	0.98
		(p = 1.2 × 10−13)		(p = 0.00091)		(p = 8.9 × 10−12)		(p = 0.00002)

^a Indicated are means ± SD of Ct values in each group. Note that Ct values follow a log₂ scale (i.e., a difference in Ct values of 1 means a twofold change in abundance);

^b sham (no shock) groups were treated with saline or with enoxacin 10 or 25 mg/kg for 1 week; t-test p values are in parentheses.