Table 2.
Escape latency of individual rats when given no shock or inescapable shock and simultaneously treated with saline or enoxacin (10 or 25 mg/kg).
| Treatment | Escape latency (s) | Response to shock | Enoxacin (mg/kg) | Escape latency (s) | Response to shock | Enoxacin (mg/kg) | Escape latency (s) | Response to shock | |
|---|---|---|---|---|---|---|---|---|---|
| Sham (no shock) | Saline | 3.27 | 10 | 2.76 | 25 | 4.22 | |||
| Sham (no shock) | Saline | 4.41 | 10 | 3.15 | 25 | 3.29 | |||
| Sham (no shock) | Saline | 4.63 | 10 | 5.22 | 25 | 4.37 | |||
| Sham (no shock) | Saline | 2.68 | 10 | 3.17 | 25 | 5.82 | |||
| Shock | Saline | 26.13 | LH | 10 | 21.36 | LH | 25 | 17.19 | NLH |
| Shock | Saline | 26.53 | LH | 10 | 23.78 | LH | 25 | 3.91 | NLH |
| Shock | Saline | 27.15 | LH | 10 | 8.62 | NLH | 25 | 8.66 | NLH |
| Shock | Saline | 30.46 | LH | 10 | 4.47 | NLH | 25 | 2.83 | NLH |
| Shock | Saline | 28.22 | LH | 10 | 1.68 | NLH | 25 | 3.96 | NLH |
| Shock | Saline | 27.34 | LH | 10 | 12.27 | NLH | 25 | 5.32 | NLH |
| Shock | Saline | 11.9 | NLH | 10 | 2.78 | NLH | 25 | 7.14 | NLH |
| Shock | Saline | 3.9 | NLH | 10 | 3.82 | NLH | 25 | 12.86 | NLH |
| Shock | Saline | 6.18 | NLH | ||||||
| Shock | Saline | 4.19 | NLH |
For rats exposed to shock, escape latency <20 s = non-learned helpless (NLH); ≥20 s = learned helpless (LH). As a baseline control, sham rats were given no shock on day 6 but were tested for escape latency on day 7.