Table 1.
Patient characteristics according to renal function as measured using the glomerular filtration rate (eGFR)
| Characteristic | eGFR ≥ 90 mL/min/1.73 m2 (N = 483) | eGFR < 90 mL/min/1.73 m2 (N = 362) | P-value |
|---|---|---|---|
| Age (years) (mean ± SEM) | 37.0 ± 0.5 | 43.5 ± 0.5 | < 0.01 |
| Gender | |||
| Male | 294 (60.9) | 244 (67.4) | 0.05 |
| Female | 189 (39.1) | 118 (32.6) | |
| Race | |||
| Caucasian | 123 (25.5) | 163 (45.0) | < 0.01 |
| African-American | 349 (72.3) | 192 (53.0) | |
| Hispanic | 11 (2.3) | 7 (1.9) | |
| Body mass index (kg/m2) (mean ± SEM) | 27.4 ± 0.3 | 27.5 ± 0.4 | 0.82 |
| Injecting drug use | 20 (4.1) | 21 (5.8) | 0.33 |
| CD4 count (cells/μL) (mean ± SEM) | |||
| Current | 419 ± 13 | 447 ± 16 | 0.16 |
| Nadir | 225 ± 10 | 198 ± 10 | 0.06 |
| On HAART | 279 (57.8) | 253 (69.9) | < 0.01 |
| HIV RNA < 400 copies/mL | 210 (75.3) | 200 (80.2) | 0.30 |
| Presence of proteinuria (n = 534) | 78 (25.2) | 80 (35.7) | < 0.01 |
| Diagnosis of hypertension | 123 (25.5) | 156 (43.1) | < 0.01 |
| Diagnosis of diabetes | 22 (4.6) | 27 (7.5) | 0.10 |
| Chronic hepatitis B | 21 (4.3) | 20 (5.5) | 0.52 |
| Chronic hepatitis C | 50 (10.4) | 49 (13.5) | 0.16 |
| Diagnosis of opportunistic infection | |||
| Current | 25 (5.2) | 20 (5.5) | 0.22 |
| Prior history | 119 (24.6) | 108 (29.8) | |
| Fasting total cholesterol (mg/dL) (mean ± SEM) | 175.5 ± 2.2 | 186.4 ± 3.1 | < 0.01 |
| Fasting LDL (mg/dL) (mean ± SEM) | 101.0 ± 2.2 | 106.1 ± 3.1 | 0.17 |
| Fasting HDL (mg/dL) (mean ± SEM) | 47.9 ± 0.9 | 47.2 ± 1.1 | 0.65 |
| Fasting TG (mg/dL) (mean ± SEM) | 149.6 ± 6.5 | 183.0 ± 8.4 | < 0.01 |
Values are n (%), unless otherwise indicated.
HDL, high-density lipoprotein; LDL, low-density lipoprotein; SEM, standard error of the mean; TG, triglycerides.