Table 1.
SNP | Cytoband | Alleles | Minor allele | MAF | Cases | Controls | Group | ORadj | (95% CI) |
Ptrend | |
---|---|---|---|---|---|---|---|---|---|---|---|
rs10936599 | 3q26.2 | T/C | T | 0.24 | 2415 | 5751 | NCI-GWAS2 | 0.81 | 0.73 | 0.89 | |
0.24 | 3517 | 5107 | NCI-GWAS1 | 0.88 | 0.81 | 0.94 | |||||
0.24 | 969 | 957 | TXBCS-GWAS | 0.84 | 0.72 | 0.98 | |||||
0.25 | 790 | 1293 | TXBCS-TaqMan | 0.90 | 0.77 | 1.05 | |||||
7691 | 13 108 | Combined | 0.85 | 0.81 | 0.90 | 4.53 × 10−9 | |||||
rs907611 | 11p15.5 | G/A | A | 0.31 | 2379 | 5720 | NCI-GWAS2 | 1.25 | 1.14 | 1.36 | |
0.33 | 2757 | 4314 | NCI-GWAS1 | 1.12 | 1.04 | 1.2 | |||||
0.32 | 968 | 955 | TXBCS-GWAS | 1.20 | 1.04 | 1.39 | |||||
0.31 | 797 | 1291 | TXBCS-TaqMan | 0.97 | 0.84 | 1.12 | |||||
6901 | 12 280 | Combined | 1.15 | 1.09 | 1.21 | 4.11 × 10−8 | |||||
rs6104690 | 20p12.2 | G/A | G | 0.44 | 2409 | 5747 | NCI-GWAS2 | 0.89 | 0.82 | 0.96 | |
0.44 | 3510 | 5097 | NCI-GWAS1 | 0.89 | 0.84 | 0.95 | |||||
0.45 | 969 | 957 | TXBCS-GWAS | 0.91 | 0.79 | 1.04 | |||||
0.46 | 790 | 1287 | TXBCS-TaqMan | 0.89 | 0.78 | 1.02 | |||||
7678 | 13 088 | Combined | 0.89 | 0.85 | 0.93 | 7.13 × 10−7 | |||||
rs4510656 | 6p22.3 | C/A | A | 0.45 | 2416 | 5747 | NCI-GWAS2 | 0.87 | 0.8 | 0.95 | |
0.43 | 3515 | 5106 | NCI-GWAS1 | 0.91 | 0.85 | 0.97 | |||||
0.45 | 968 | 957 | TXBCS-GWAS | 0.88 | 0.77 | 1.01 | |||||
0.46 | 798 | 1300 | TXBCS-TaqMan | 0.90 | 0.79 | 1.03 | |||||
7697 | 13 110 | Combined | 0.89 | 0.85 | 0.93 | 6.98 × 10−7 |
OR adjusted for age, study group, smoking status and gender. Fixed-effects meta-analysis by stage was used to calculate the combined OR, 95% CI and P-trend.