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. 2013 Oct 24;23(5):1387–1398. doi: 10.1093/hmg/ddt519

Table 1.

Associations for rs10936599 at 3q26.2, rs907611 at 11p15.5, rs6104690 at 20p12.2 and rs4510656 at 6p22.3 with bladder cancer risk

SNP Cytoband Alleles Minor allele MAF Cases Controls Group ORadj (95% CI)
Ptrend
rs10936599 3q26.2 T/C T 0.24 2415 5751 NCI-GWAS2 0.81 0.73 0.89
0.24 3517 5107 NCI-GWAS1 0.88 0.81 0.94
0.24 969 957 TXBCS-GWAS 0.84 0.72 0.98
0.25 790 1293 TXBCS-TaqMan 0.90 0.77 1.05
7691 13 108 Combined 0.85 0.81 0.90 4.53 × 10−9
rs907611 11p15.5 G/A A 0.31 2379 5720 NCI-GWAS2 1.25 1.14 1.36
0.33 2757 4314 NCI-GWAS1 1.12 1.04 1.2
0.32 968 955 TXBCS-GWAS 1.20 1.04 1.39
0.31 797 1291 TXBCS-TaqMan 0.97 0.84 1.12
6901 12 280 Combined 1.15 1.09 1.21 4.11 × 10−8
rs6104690 20p12.2 G/A G 0.44 2409 5747 NCI-GWAS2 0.89 0.82 0.96
0.44 3510 5097 NCI-GWAS1 0.89 0.84 0.95
0.45 969 957 TXBCS-GWAS 0.91 0.79 1.04
0.46 790 1287 TXBCS-TaqMan 0.89 0.78 1.02
7678 13 088 Combined 0.89 0.85 0.93 7.13 × 10−7
rs4510656 6p22.3 C/A A 0.45 2416 5747 NCI-GWAS2 0.87 0.8 0.95
0.43 3515 5106 NCI-GWAS1 0.91 0.85 0.97
0.45 968 957 TXBCS-GWAS 0.88 0.77 1.01
0.46 798 1300 TXBCS-TaqMan 0.90 0.79 1.03
7697 13 110 Combined 0.89 0.85 0.93 6.98 × 10−7

OR adjusted for age, study group, smoking status and gender. Fixed-effects meta-analysis by stage was used to calculate the combined OR, 95% CI and P-trend.