Table 3.
Univariate association of candidate predictors with CIMT.
| Wilcoxon | p-value | N | Modeled? | |
|---|---|---|---|---|
| Male gender | 0.03 | 125 | Yes | |
| Prevalent cardiovascular disease | 0.10 | 125 | No | |
| Hypertension treatment | 0.19 | 125 | Yes | |
| Diabetes mellitus | 0.41 | 125 | Yes | |
| Framingam risk class | 0.007 | 125 | No |
| Rho | p-value | N | Modeled? | |
|---|---|---|---|---|
| FRS ATPIII | 0.31 | 0.0004 | 125 | Yes |
| Age | 0.31 | 0.0003 | 125 | Yes |
| Plasma HIV RNA | 0.06 | 0.51 | 125 | No |
| CD4+ T cell count | −0.04 | 0.66 | 125 | No |
| CD8+ T cell activation (% CD38+/HLA-DR+) | −0.08 | 0.38 | 108 | No |
| CD14+CD16−% or Mono 1 | −0.11 | 0.22 | 108 | No |
| CD14+CD16++ % or Mono 2 | 0.03 | 0.71 | 108 | No |
| CD14dim/−CD16++% or Mono 3 | −0.04 | 0.62 | 108 | No |
| CD14dimCD16−% or Mono 4 | 0.15 | 0.11 | 108 | Yes |
| C-RP | 0.22 | 0.01 | 121 | Yes |
| IL-6 | 0.17 | 0.06 | 121 | Yes |
| IL-8 | 0.23 | 0.02 | 121 | Yes |
| IL-10 | 0.09 | 0.31 | 121 | No |
| IL-1β | 0.07 | 0.41 | 121 | No |
| TNF | 0.13 | 0.16 | 121 | No |
| MPO | 0.04 | 0.66 | 121 | No |
| MMP-9 | −0.04 | 0.68 | 121 | No |
| tPAI-1 | 0.02 | 0.76 | 121 | No |
| NT ProBNP | 0.01 | 0.86 | 121 | No |
| sICAM-1 | 0.01 | 0.90 | 121 | No |
| sVCAM-1 | 0.25 | 0.006 | 121 | Yes |
| sE-Selectin | 0.12 | 0.19 | 121 | No |
| MCP-1 | 0.12 | 0.19 | 121 | No |
| VEGF | 0.15 | 0.10 | 121 | Yes |
| Soluble CD14 | −0.06 | 0.52 | 121 | No |
| SAA | 0.21 | 0.02 | 121 | Yes |
| SAP | 0.10 | 0.25 | 121 | No |
Abbreviations: FRS ATPIII, Framingham risk score ATPIII, C-RP = C-reactive protein, IL-6 = Interleukin-6, IL-8 = Interleukin 8, IL-10 = Interleukin-10, IL-1b = Interleukin-1 beta, TNF = tumor necrosis factor, MPO = myeloperoxidase, MMP-9 = matrix metalloproteinase 9, tPAI-1 = tissue plasminogen activator inhibitor-1, NT ProBNP = N-terminal fragment of brain natriuretic peptide, sICAM-1 = soluble intercellular cell adhesion molecule 1, sVCAM-1 = soluble vascular adhesion molecule 1, sE-Selectin = soluble E (CD62E), endothelial-leukocyte adhesion molecule 1, MCP-1 = monocyte chemoattractant protein 1, soluble CD14 = free plasma CD14, SAA = serum amyloid alpha, SAP = serum amyloid P.