Sample size |
22 |
Donor age |
62 (45–76) |
Weight (kg) |
101.4 (57.7–129.5) |
Males |
16 |
Females |
6 |
Co-morbidity and medications |
% |
Donors with diabetes |
52.6 |
Donors with prior myocardial infarction |
75.1 |
Donors on angiotensin-converting enzyme inhibitor |
56.2 |
Donors on beta-blockers |
94 |
Donors on statins |
90.4 |
Severity of coronary artery disease |
Mean (SD) |
Prior percutaneous coronary intervention (PCI) |
2.9 (3.1) |
Prior coronary artery bypass graft (CABG) |
1.3 (0.6) |
SPECT left ventricular ejection fraction (LVEF) |
60.1 (14) |
Cell counts and viability |
Median (range) |
Peripheral blood CD34+ cell count/μL |
22.6 (10.7–71.2) |
Pre-selection total nucleated cell × 108/kg |
3.1 (1.22–6.69) |
Pre-selection CD34+ cell × 106/kg |
0.79 (0.09–3.53) |
Pre-selection cell viability (%) |
98 (90–99) |
Post-selection CD34+ cell (%) |
82.5 (47–95.8) |
Expression of differentiation markers |
Median (range) |
Post-selection T cells (CD3+) (%) |
1 (0.2–2) |
Post-selection B cells (CD20+) (%) |
5.5 (2–23) |
Post-selection platelets/megakaryocytes (CD41+) (%) |
15 (4–81) |