Table V.
Effect of CD34+ cell selection on MNC characteristics.
| Antigen | Description | Pre-selection | Post-selection | P-value |
|---|---|---|---|---|
| Cell type | Median | Median | ||
| Product volume (mL) | 327 | 100 | ||
| TNC × 106 | 32517 | 108.3 | ||
| CD3+ (%) | T cell | 6 | 1 | <0.01 |
| CD20+ (%) | Early B cell | 1 | 5.5 | <0.01 |
| CD41+ (%) | Megs/platelets | 39 | 15 | 0.39 |
| CD309+ (%) | VEGFR/KDR | 14 | 3 | 0.39 |
| CD339 (%) | Notch/Jagged-1 | 2 | 4 | <0.01 |
| CD133+ (%) | HSC | 0.5 | 51 | <0.01 |
| CD34 subsets | ||||
| CD34+ CD133+ (%) | Immature CD34 | 64 | 71 | 0.31 |
| CD34+ CD309+ (%) | EPC | 79 | 2 | 0.05 |
| CD34+ CD339+ (%) | – | 46 | 3.6 | 0.04 |
| CD34+ CD41+ | Megakaryocyte progenitor | 84 | 30 | 0.02 |