Figure 4.

Structural Features Shared by P23-77 and SH1

Structure of VP16 dimer fitted into the cryo-EM electron density maps of the P23-77 virion (Jaatinen et al., 2008) and SH1 virion (Jäälinoja et al., 2008).

(A) VP16 in P23-77 virion density.

(B) Asymmetric unit of P23-77, showing the position of protruding VP17 turret proteins (green circles) and VP16 (pale beige circles).

(C) VP16 in SH1 density, at the same position as in (A).

(D) Asymmetric unit of SH1, showing the position of protruding equivalent turret proteins (blue circles). VP16 spans across capsomer borders in P23-77, causing bridges of density in the cryo-EM map. These bridges are found in identical position in P23-77 and SH1 and are illustrated here and in (B) as red bars. Note that, in SH1, every bridge connects a turreted protein to either a turreted or nonturreted protein.

See also Table S1.