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. 2013 Dec 31;70(Pt 1):165–176. doi: 10.1107/S1399004713027910

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© Ruskamo et al. 2014

This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.

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Crystal structure of human P2. (a) Overall structure of human P2. (b) Electron density for the ligands cis-vaccenate (magenta) and palmitate (cyan). The final refined 2F _o − F _c map is contoured at 1.5σ. OMIT maps calculated without palmitate are shown in Supplementary Fig. S2. (c) Orientation of the fatty-acid COOH group. The 2F _o − F _c map (5.5σ) is shown. (d) The difference map, calculated without H atoms (green, 1.7σ; magenta, 2.5σ). The lost proton in Arg106 is indicated by the arrow.