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Confirmation of the deletion by FISH in an interphase nucleus (upper left) and a metaphase nucleus: the RP11-574D15 probe (spectrum green, white arrow) shows only one signal in the normal chromosome 2 (2q12.1 locus). The 2q telomeric probe (spectrum orange, Abbott Molecular, Ottignies, Belgium) shows 2 normal signals (2 split signals in interphase nucleus).
