Table 1. Body weight, cardiac arrest parameters, survival rate, and general health assessment.
Total ischemia represents time from induction of cardiac arrest to successful resuscitation. Postoperative day (POD) refers to day following CA/CPR.
CA 6 minutes | CA 8 minutes | ||||
---|---|---|---|---|---|
Adult | Pediatric | Adult | Pediatric | ||
Nomothermia | Hypothermia | ||||
N | 8 | 6 | 7 | 8 | 6 |
Body weight (BW, g) | 23.2 ± 0.6 | 9.7 ± 0.2 | 23.6 ± 0.6 | 9.9 ± 0.4 | 10.3 ± 0.2 |
Total ischemia time (sec) | 461 ± 7 | 436 ± 5 | 590 ± 6 | 594 ± 7 | 590 ± 9 |
Epinephrine (µg/g BW) | 0.26 ± 0.03 | 0.42 ± 0.02* | 0.33 ± 0.04 | 0.52 ± 0.05* | 0.52 ± 0.07 |
Surviving animals (%) | 89(8/9) | 100(6/6) | 70(7/10) | 89(8/9) | 100(6/6) |
Health Assessment Score | |||||
POD 1 | 1.6 ± 0.3 | 1.0 ± 0.5 | 4.9 ± 0.8* | 2.1 ± 0.3 | 2.2 ± 0.2 |
POD 2 | 1.1 ± 0.2 | 0.2 ± 0.2 | 2.0 ± 0.8 | 1.4 ± 0.3 | 1.5 ± 0.2 |
POD 3 | 0.5 ± 0.2 | 0.0 ± 0.0 | 2.1 ± 1.2* | 0.5 ± 0.2 | 0.7 ± 0.2 |
* in epinephrine indicates P < 0.05 compared to corresponding adult group and * in health assessment score indicates P < 0.05 compared to pediatric normothermia 8 minute group.
CA/CPR, cardiac arrest and cardiopulmonary resuscitation. BW, body weight.