Figure 7. S100A1 Ameliorates Abnormal High-Energy Phosphate Content and Mitochondrial Electron Flow in HFCMs.
(A) Normalization of S100A1 in HFCMs resulted in a restored PC/ATP ratio reflecting ameliorated cellular energy homeostasis. (B) Superior electron flow in isolated mitochondria from S100A1-expressing HFCMs under basal conditions (buffer) and experimental Ca2+ stress (CaCl2 100 µmol/l) as assessed by MTT reduction. Abbreviations as in Figure 1.