Table 3.
Hemodynamic and ventilatory parameters |
CHF patients (N=7) |
Controls (N=8) |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | CPAP 5 cm H2O start |
CPAP 5 cm H2O end |
CPAP 10 cm H2O start |
CPAP 10cm H2O end |
Recovery | Baseline | CPAP 5 cm H2O start |
CPAP 5 cm H2O end |
CPAP 10 cm H2O start |
CPAP 10cm H2O end |
Recovery | ||
MAP (mmHg) | Mean SD |
84.1† 12 |
82.8 11 |
86.4 15 |
84.0 12 |
83.3 13 |
84.4 14 |
97.8 8 |
100.2 9 |
101.8 9 |
102.3 7 |
102.9 8 |
99.7 9 |
SBP(mmHg) | Mean SD |
122.5† 21 | 135.5* 26 |
135.0* 23 |
131.6* 16 |
130.1* 15 |
133.5 26 |
148.0 19 |
153.5 23 |
156.2 23 |
158.7 21 |
157.5 20 |
150.1 23 |
DBP (mmHg) | Mean SD |
63.4 8 |
66.2 12 |
65.4 13 |
64.8 13 |
63.8 13 |
64.8 11 |
71.1 7 |
74.7* 6 |
75.2 5 |
77.1* 4 |
77.4* 6 |
73.2 6 |
SV (ml) | Mean SD |
94.5 19 |
91.1 22 |
90.1 23 |
92.1 23 |
93.6 25 |
95.8 22 |
111.0 17 |
101.7* 14 |
102.1* 10 |
96.5* 12 |
95* 12 |
105.5 14 |
HR (bpm) | Mean SD |
64 7 |
65 8 |
63 7 |
68 5 |
68 6 |
64 7 |
67 8 |
66 7 |
66 7 |
65 7 |
66 12 |
65 7 |
CO (l/min) | Mean SD |
6.1 2 |
5.9 1 |
5.7 2 |
6.1 1 |
6.3 2 |
6.1 1 |
7.5 2 |
6.7 1 |
6.7* 1 |
6.2* 1 |
6.2* 1 |
6.8 1 |
VT (ml) | Mean SD |
640 382 |
700 220 |
800 550 |
951 556 |
980 560 |
520 392 |
825 106 |
1274* 385 |
1177 407 |
1358* 277 |
1155* 322 |
769 116 |
Bf(bpm) | Mean SD |
16 6 |
16 7 |
16 7 |
19 9 |
16 10 |
19 8 |
12 3 |
13 3 |
15* 3 |
16* 4 |
16* 4 |
12 3 |
VE (l/min) | Mean SD |
8.8 3 |
10.1 3 |
10.4 5 |
14.8 5 |
12.7 5 |
8.1 4 |
10.0 2 |
16.7* 4 |
16.8* 5 |
20.7* 6 |
7.8* 4 |
9.9 3 |
MAP indicates mean arterial pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; SV, stroke volume; HR, heart rate; CO, cardiac output; VT, tidal volume; Bf, breathing frequency; VE, ventilatory volume.
p <0.05 different from baseline.
p <0.05 different from controls.