. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: Genes Brain Behav. 2013 Dec 26;13(2):213–225. doi: 10.1111/gbb.12113

Table 2.

Quantitative RT-PCR confirms differential insulin-related gene expression in the NAc of α7 KO and WT mice.

Gene	Normalized Relative KO Expression	KO SEM	Normalized Relative WT Expression	WT SEM	p-value

Ide	0.731	0.091	1.102	0.096	1.55E-02
Igfbp2	1.768	0.249	1.166	0.166	1.08E-01
Igfbp6	1.549	0.144	1.071	0.136	3.58E-02
Ndn	2.374	0.160	1.177	0.078	3.09E-03

Basal mRNA expression of Ide is significantly down-regulated in the NAc of KO mice compared to WT mice, while Igfbp6 is significantly up-regulated, and there is a trend toward up-regulation of Igfbp2. Each point represents the mean of ± SEM (n_KO=4 and n_WT=5). All genes were normalized to the housekeeping gene, Gapdh.