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. Author manuscript; available in PMC: 2014 Feb 10.
Published in final edited form as: Glia. 2013 Jul 10;61(9):1500–1517. doi: 10.1002/glia.22537

FIGURE 8.

FIGURE 8

LOV-mediated protective effects were lacking in PPAR-α-deficient OLs exposed to cytokines. OLs from wild type (WT) and PPAR-α(–/–) mice were exposed to TNF plus IL-17 and LOV as detailed in the Fig. 1 legend. (A) The composite mean ± SE of three to four samples analyzed in triplicate depicts LDH release in the culture supernatants of treated OLs for 96 h. (B) The composite mean ± SE of three to four slides analyzed in triplicate depicts a MBP+ve OLs/field of the slide in treated OLs for 96 h. Statistical significance as indicated in Fig. 1 legend.