Table 4.
Performance of DR_bind1 based on 41 ribosomal (or 40 nonribosomal) RNA-bound protein structures compared to that of KYG, OPRA, BindN+ or Pprint for the same number of predictions made by DR_bind1a
| DR_bind1 | KYG | OPRA | BindN+ | Pprint | |
|---|---|---|---|---|---|
| TP | 102 (64) | 82 (33) | 76 (26) | 97 (59) | 90 (48) |
| FP | 19 (56) | 39 (87) | 45 (94) | 24 (61) | 31 (72) |
| TN | 3673 (10 955) | 3653 (10 924) | 3647 (10 917) | 3668 (10 950) | 3661 (10 939) |
| FN | 1883 (1009) | 1903 (1040) | 1909 (1047) | 1888 (1014) | 1895 (1025) |
| Sensitivity | 0.05 (0.06) | 0.04 (0.03) | 0.04 (0.02) | 0.05 (0.05) | 0.05 (0.04) |
| Specificity | 0.99 (0.99) | 0.99 (0.99) | 0.99 (0.99) | 0.99 (0.99) | 0.99 (0.99) |
| Precision | 0.84 (0.53) | 0.68 (0.28) | 0.63 (0.22) | 0.80 (0.49) | 0.74 (0.40) |
| Accuracy | 0.66 (0.91) | 0.66 (0.91) | 0.66 (0.91) | 0.66 (0.91) | 0.66 (0.91) |
| MCC | 0.15 (0.16) | 0.10 (0.07) | 0.09 (0.05) | 0.14 (0.14) | 0.12 (0.11) |
aNumbers with and without parentheses were derived from 40 nonribosomal and 41 ribosomal RNA-bound protein structures, respectively.