Table 5.
Performance of DR_bind1 based on 41 ribosomal (or 40 nonribosomal) RNA-bound protein structures compared to that of dRNA-3Da
| Homolog structures | DR_bind1 |
dRNA-3D |
||
|---|---|---|---|---|
| Noneb | No complexc | Best complexd | Second best complexe | |
| TP | 110 (74) | 101 (58) | 1950 (873) | 1295 (627) |
| FP | 24 (66) | 22 (54) | 173 (321) | 463 (681) |
| TN | 3668 (10 945) | 3670 (10 957) | 3519 (10 690) | 3229 (10 330) |
| FN | 1875 (999) | 1884 (1015) | 35 (200) | 690 (446) |
| Sensitivity | 0.06 (0.07) | 0.05 (0.05) | 0.98 (0.81) | 0.65 (0.58) |
| Specificity | 0.99 (0.99) | 0.99 (1) | 0.95 (0.97) | 0.87 (0.94) |
| Precision | 0.82 (0.53) | 0.82 (0.52) | 0.92 (0.73) | 0.74 (0.48) |
| Accuracy | 0.67 (0.91) | 0.66 (0.91) | 0.96 (0.96) | 0.80 (0.91) |
| MCC | 0.15 (0.17) | 0.15 (0.15) | 0.92 (0.75) | 0.54 (0.48) |
aNumbers with and without parentheses were derived from 40 nonribosomal and 41 ribosomal RNA-bound protein structures, respectively.
bNumbers were derived without free/complex structures of homologs.
cNumbers were derived without complex structures of homologs.
dNumbers were derived based on the best matching complex structure.
eNumbers were derived based on the second best matching complex structure.