Table 1.

Correlation between the presence of the negatively charged regions on octamer-facing surface of RNAPs, the height of the nucleosomal barrier and nucleosome survival during transcription

Enzyme	Species	ZLS regions net chargea	Ø-loop at +49	Height of +45 barrier	Nucleosome survival
Pol II (RPB1)	H. sapiens	−8	ND	+++++b	ND
Pol II (Rpb1)	S. cerevisiae	−15	+c	+++++b	+++++d
RNAP (β′)	T. thermophilus	+1	ND	+e	ND
RNAP (β′)	T. aquaticus	+1	−e	+e	–

^aThe net charge of the region homologous to the ZLS region 1434–1450 of Rpb1 subunit of yeast Pol II.

^bReference (34).

^cReference (20).

^dReference (32).

^eThis work.