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Survival plot of all male and female WT and PC2-ko mice during 18-month study duration. Note that no WT animals died during the study whilst 13 male and female PC2-ko mice died prematurely between 6.5 and 14 months; the remainder survived to scheduled termination. n/sex/time for WT and PC2-ko male and female animals: 10 (3 months), 15 (12 and 18 months).
