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. Author manuscript; available in PMC: 2014 Feb 10.
Published in final edited form as: Gene. 2013 Mar 21;521(1):78–81. doi: 10.1016/j.gene.2013.03.022

Table 2.

Sib-TDT analysis of LRP8 SNPs for association with CAD in GeneQuest and GeneQuest II.

Risk allele Minor alleles Z-score P-value
GeneQuest
rs7546246 C 181 2.98 0.002
rs2297660 A 190 1.89 0.040
rs3737983 T 194 3.46 3.0 × 10−4
rs5177 G 181 3.81 5.0 × 10−5
GeneQuest II
rs7546246 C 67 2.15 0.016
rs2297660 A 72 2.70 0.004
rs3737983 T 67 2.15 0.016
rs5177 G 72 2.70 0.004

Minor alleles: the number of minor alleles among affected sibs across all sibships.