Figure 3. Effect of mature miR-195 and miR-497 transfection of BC cell lines (BOY, T24).

Gain-of-function studies were performed by using miR-195 and miR-497-transfected BOY and T24 in comparison with the miR-control transfectants. A) Cell proliferation determined by the XTT assay. B) Cell invasion activity demonstrated by the Matrigel invasion assay. C) Cell migration activity determined by the wound healing assay. *, P<0.0001; **, P = 0.009.