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. 2014 Feb 10;9(2):e84311. doi: 10.1371/journal.pone.0084311

Figure 7. BIRC5 and WNT7A as target genes of the miR-195/497 cluster in BC.

Figure 7

Luminescence intensity was measured in miR-195- and miR-497-transfectants in comparison with the miR-control transfectant. A) miR-195/497 cluster binding sites in the 3′-UTR of BIRC5 mRNA. Luciferase reporter assay vector used the encoding 3′-UTR region of BIRC5 including putative miR-195/497 target sites. Renilla luciferase values were normalized to firefly luciferase values. *P<0.01. B) miR-195/497 cluster binding sites in the 3′-UTR of WNT7A mRNA. Luciferase reporter assay vector is the encoding 3′-UTR region of WNT7A including putative miR-195/497 target site. *P<0.01.