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. 2014 Feb 10;9(2):e87230. doi: 10.1371/journal.pone.0087230

Figure 2. Three month-old male whole body glucose, insulin and pyruvate tolerance.

Figure 2

Whole body tolerance tests were completed on fasted three month-old male wildtype (WT) and aromatase knockout (KO) and 2.5 µg/day 17β-estradiol-treated KO (KOE) (a) glucose tolerance test and corresponding area under curve; (b) insulin tolerance test and corresponding area under curve; (c) pyruvate tolerance test and corresponding area under curve Data are presented from replicate analysis (n =  shown on corresponding bar) as the mean ± SD. *p<0.05, **p<0.01, ***p<0.001, versus expression in age-matched WT samples and #p<0.05 and ##p<0.01 versus KO samples.