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. 2014 Feb 10;9(2):e87169. doi: 10.1371/journal.pone.0087169

Table 2. Estimates of the parameters defining the age-dependent pyrogenic threshold of P. ovale infections during the period 1990–2004.

Parameters Period 1990–2004
Number of individuals 617
Number of case observations 12,182
Number of control observations 37,074
Exponent for the function of parasitemia (r) 0.52
Age in years of maximum parasitemia (a) 4
Maximum threshold parasitemia (b) 3800
Parasitemia at year 0 (c) 100
Lowest threshold parasitemia in adults (d) 350
Decay parameter of the function (e) 0.09
Threshold effect odds ratios (95% CI) 5.6 (2.2–13.9)
Continuous effect of parasitemia odds ratios for an increase of 100 parasites/µl (95% CI) 1.4 (1.2–1.5)
0–1 year old effect odds ratios 1.0
2–6 years old effect odds ratios (95% CI) 1.9 (1.8–2.1)
7–12 years old effect odds ratios (95% CI) 1.9 (1.7–2.1)
≥13 years old effect odds ratios (95% CI) 2.0 (1.7–2.3)
AIC 47315.0