Table 1. Anthropometric parameters, semen characteristics, seminal antioxidant markers, metabolic and hormonal profiles and pregnancy outcome at baseline and after dietary advices.
Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Wilcoxon test | |||||||
baseline | after diet | baseline | after diet | baseline | after diet | baseline | after diet | baseline | after diet | baseline | after diet | signification (alpha s) | |
Anthropometry | |||||||||||||
age (years) | 30 | 29 | 33 | 28 | 27 | 44 | |||||||
height (m) | 1.86 | 1.82 | 1.89 | 1.73 | 1.88 | 1.89 | |||||||
weight (kg) | 87.5 | 86.2 | 93.7 | 87.7 | 160.6 | 146.7 | 79.5 | 78.4 | 96.2 | 94.7 | 111.6 | 109 | 0.0139* |
BMI (kg/m2) | 25.3 | 24.9 | 28.3 | 26.5 | 44.9 | 41.1 | 26.6 | 26.2 | 27.2 | 26.8 | 31.2 | 30.7 | 0.0139* |
waist circunference (cm) | 103 | 90 | 90 | 89 | 142 | 121 | 83 | 80 | 96 | 94 | 125 | 114 | 0.0139* |
intra-abdominal fat | 6 | 3 | 4 | 3 | 26 | 13 | 6 | 3 | 7 | 5 | 13 | 9 | 0.0139* |
Sperm analysis | |||||||||||||
total sperm count (M) | 28.4 | 16.9 | 76.2 | 31.9 | 35.6 | 87 | 74 | 199.6 | 29 | 176.6 | 21.9 | 32 | 0.1244 |
progressive sperm motility (%) | 40 | 40 | 30 | 30 | 8 | 10 | 40 | 25 | 25 | 45 | 8 | 35 | 0.1367 |
normal spermatozoa (%) | 31 | 27 | 14 | 15 | 11 | 21 | 26 | 19 | 7 | 14 | 11 | 16 | 0.2068 |
sperm fragmentation (%) | 31 | 9.5 | 66 | 26.3 | 25 | 1.7 | 43 | 24 | 47 | 18 | 35 | 25.4 | 0.0139* |
Seminal plasma analysis | |||||||||||||
superoxide dismutase protein 2 (pg/ml) | 1191.5 | 2741.5 | 809 | 3621.5 | 1819 | 3311.5 | 4191.5 | >4399 | 754 | 3499 | 2939 | 4484 | 0.0139* |
Biological parameters | |||||||||||||
fasting glucose (g/l) | 0.9 | 0.83 | 0.82 | 1.01 | 0.94 | 0.92 | 0.88 | 0.87 | 0.95 | 0.97 | 0.97 | 0.83 | 0.3766 |
triglycerides (g/l) | 0.82 | 0.7 | 0.89 | 0.59 | 1.87 | 1.39 | 1.02 | 0.7 | 1.21 | 1.1 | 3.07 | 2.19 | 0.0139* |
total cholesterol (g/l) | 2.01 | 1.72 | 2.2 | 1.64 | 1.75 | 1.62 | 2.01 | 1.69 | 1.86 | 1.64 | 3.17 | 2.63 | 0.0139* |
HDL (g/l) | 0.46 | 0.37 | 0.52 | 0.37 | 0.43 | 0.54 | 0.47 | 0.38 | 0.51 | 0.5 | 0.62 | 0.5 | 0.0865 |
LDL (g/l) | 1.4 | 1.21 | 1.51 | 0.95 | 0.96 | 0.97 | 1.35 | 1.17 | 1.11 | 1.52 | 2.11 | 1.52 | 0.1244 |
HDL/LDL ratio | 0.33 | 0.31 | 0.34 | 0.39 | 0.45 | 0.56 | 0.35 | 0.32 | 0.46 | 0.33 | 0.29 | 0.33 | |
FSH (UI/l) | 4.6 | 3.2 | 4.6 | 4.5 | 3.6 | 3.2 | 2.1 | 2.3 | 45 | 4.1 | 2.6 | 2.3 | 0.0374* |
LH (UI/l) | 5.3 | 2.7 | 4.9 | 4.8 | 3.9 | 2.7 | 3 | 2.7 | 3.3 | 2.9 | 2.3 | 2.7 | 0.0865 |
oestradiol (pg/ml) | 51.7 | 36 | 37.4 | 22 | 34.6 | 32.8 | 32.8 | 26 | 30.3 | 28 | 26.7 | 18.1 | |
testosterone (ng/ml) | 2.31 | 5.2 | 1.81 | 5.52 | 1.83 | 2.78 | 5.07 | 5.82 | 2.07 | 3.8 | 1.53 | 2.06 | |
testo/oestra ratio | 44.6 | 144.4 | 48.4 | 250.9 | 52.9 | 87.76 | 154.6 | 223.8 | 68.3 | 135.7 | 57.3 | 113.8 | 0.0139* |
Assisted reproductive treatment | 1 stim 1 IUI | 1 IUI | 1 stim | 1 IUI | 2 stim 1 IUI | 1 IUI | 1 stim 3 IUI | 1 IUI | 2 stim | None | 3 IUI | 1 IUI | |
Outcome | No pregnancy | Live birth | No pregnancy | Live birth | No pregnancy | Live birth | No pregnancy | Live birth | No pregnancy | Live birth | No pregnancy | Live birth |