Table 3. Inflammation-related genes that were upregulated by more than 2-fold at both 1 and 3 weeks after SCI.
Gene symbol | Gene full name | Log2 (fold change) | ||
1 week | 3 week | TMT | ||
Lgals3 | lectin, galactoside-binding, soluble, 3 | 2.53 | 3.41 | 3.34 |
C3 | complement component 3 | 2.25 | 1.64 | 1.62 |
Cd68 | Cd68 molecule | 2.20 | 2.61 | 2.58 |
Cd86 | Cd86 molecule | 2.20 | 2.61 | 1.39 |
Aif1 | allograft inflammatory factor 1 | 2.13 | 1.73 | 1.77 |
Timp1 | TIMP metallopeptidase inhibitor 1 | 2.11 | 1.87 | 1.63 |
Ly86 | lymphocyte antigen 86 | 2.03 | 1.34 | 1.44 |
Cfh | complement factor H | 1.74 | 1.88 | 1.76 |
Ptprc | protein tyrosine phosphatase, receptor type, C (CD45) | 1.74 | 1.14 | 1.30 |
Blnk | B-cell linker (Ly57) | 1.72 | 1.60 | 1.72 |
Tifab | TRAF-interacting protein with forkhead-associated domain, family member B | 1.66 | 1.16 | 1.35 |
Csf3r | colony stimulating factor 3 receptor (granulocyte) | 1.63 | 1.30 | 1.42 |
Hmox1 | heme oxygenase (decycling) 1 | 1.59 | 1.06 | 0.83 |
Klhl6 | kelch-like family member 6 | 1.53 | 1.04 | 1.01 |
Pycard | PYD and CARD domain containing | 1.44 | 1.11 | 1.19 |
C1qb | complement component 1, q subcomponent, B chain | 1.44 | 1.49 | 1.46 |
Itgal | integrin, alpha L | 1.42 | 1.14 | 1.54 |
Nckap1l | NCK associated protein 1 like (Hem1) | 1.42 | 1.18 | 1.04 |
Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 (Shp1) | 1.38 | 1.29 | 1.23 |
Fcgr2a/2b | Fc fragment of IgG, low affinity lia/b, receptor (CD32) | 1.36 | 1.51 | 1.76 |
Cd53 | Cd53 molecule | 1.34 | 1.25 | 1.36 |
C1qa | complement component 1, q subcomponent, A chain | 1.33 | 1.46 | 1.37 |
C2 | complement component 2 | 1.33 | 1.40 | 1.16 |
Inpp5d | inositol polyphosphate-5-phosphatase D (Ship1) | 1.26 | 1.21 | 1.16 |
Csf1r | colony stimulting factor 1 receptor | 1.26 | 1.10 | 1.28 |
Mall | mal, T-cell differentiation protein-like | 1.18 | 1.37 | 1.41 |
Anxa3 | annexin A3 | 1.15 | 1.00 | 1.13 |
Mrc2 | mannose receptor, C type 2 | 1.13 | 1.36 | 1.21 |
Cyba | cytochrome b-245, alpha polypeptide (p22-phox) | 1.12 | 1.11 | 1.23 |
C1qc | complement component 1, q subcomponent, C chain | 1.10 | 1.04 | 1.18 |
Itgb2 | integrin, beta 2 | 1.03 | 1.29 | 1.36 |
Ifitm1 | interferon induced transmembrane protein 1 | 1.01 | 1.28 | 0.80 |
TMT = treadmill locomotor training.