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Top graphs: time course of measures of up-state duration and amplitude in cultures treated with sham conditions, the TRPV1 agonist capsaicin (CAP; 3 µM), or the TRPV1 antagonist capsazepine (CPZ; 10 µM). Bottom graphs: summary data from the three treatment conditions binned over the last 10 min and normalized to their respective baselines. Bars represent mean ± SEM.
