Figure 2.

Resveratrol (Res) regulates differentiation in rabbit articular chondrocytes. Rabbit articular chondrocytes were untreated or treated (A) with various concentrations of resveratrol for 24 h or (B) with 20 μM resveratrol for the specified time periods. (C) Expression of type II collagen was determined by immunofluorescence staining and (D, upper panel) immunohistochemical staining (magnification, ×200). (D, lower panel) Sulfated proteoglycan was detected in tissue by Alcian blue staining. The data represent a typical experiment, whereby similar results were obtained from four experiments. ^*P<0.05, compared with untreated cells.