Figure 3.

Resveratrol regulates the expression of COX-2 in rabbit articular chondrocytes. Rabbit articular chondrocytes were treated (A and B) with 20 μM resveratrol for 0–72 h or (C and D) with 10–100 μM Res for 3 h. (A and C) Expression levels of COX-2 were determined by western blot analysis. Actin was used as a loading control. (B and D) The relative amounts of COX-2 were quantified by densitometric measurement (with ImageJ software). The data represent a typical experiment, whereby similar results were obtained from three experiments. ^*P<0.05, compared with untreated cells. COX-2, cyclooxygenase-2.