Figure 4.

Changes in anti-apoptotic signaling molecule expression in human gastric adenocarcinoma. (A) A representative image showing anti-apoptotic signaling molecules in human gastric adenocarcinoma using immunoblotting. The proteins were stained with antibodies against BNIP3, Bcl-2 and XIAP. (B) Quantitative analysis of protein levels was performed by densitometric analysis of the bands. Immunoblotting with an anti-actin antibody showed equal amounts of loaded protein in each lane. Data are expressed as percentages of control values (mean ± standard deviation; n=5). ^*P<0.05 and ^**P<0.01, vs. control. Con, control; GC, gastric carcinoma; Bcl-2, B-cell lymphoma 2; BNIP3, Bcl-2 and nineteen-kilodalton interacting protein-37; XIAP, X-linked inhibitor of apoptosis.