Figure 1.

The electric current of the alternating magnetic fields was controlled and the temperature of the thermoseeds was maintained within the ranges of (A) 42–46°C (H1 group) and (B) 50–55°C (H2 group). In these two hyperthermia-treated groups, the rectal temperature was maintained at 35–37°C. Following the thermal treatment, tumor growth in the H1 and H2 groups of rats was inhibited, particulary in the H2 group, and was observed on both sides of the rats. Tumor diameter was measured every 2 days to determine the growth curves of tumors on both the (C) heated side and (D) unheated side. Group C, untreated control; group M, magnetic field control; group T, thermoseed control; group H1, thermoseeds heated to 42–46°C for 30 min; group H2, thermoseeds heated to 50–55°C for 10 min.