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. 2014 Jan 16;7(3):658–662. doi: 10.3892/ol.2014.1807

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Copyright © 2014, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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miR-203 inhibits the EMT by targeting caveolin-1. Panc-1 cells were transfected with control or caveolin-1 siRNA. The cells were then treated with the miR-203 mimic for 1 day and subjected to (A) the scratch-wound assay, (B) cell invasion assays and (C) western blot analysis of Zeb-1, vimentin and fibronectin. (D) The relative proteins levels were normalized to GAPDH. The treatments in this figure were carried out in triplicate and the results are displayed as the means ± SD. GAPDH, glyceraldehyde 3-phosphate dehydrogenase; EMT, epithelial to mesenchymal transition.