. Author manuscript; available in PMC: 2014 Feb 11.

Published in final edited form as: Pediatr Blood Cancer. 2013 Aug 19;61(2):269–275. doi: 10.1002/pbc.24739

TABLE IV.

Comparison of Clinical Outcomes Within Treatment Group by Time Period

Treatment group	N	Time period	OS^a	P	Relapse^b	P	TRM	P
Poor risk: chemotherapy	46	1989–1997	39 ± 14%	0.64	65 ± 14%	0.49	7 ± 7%	0.72
Poor risk: chemotherapy	77	1998–2006	46 ± 12%		58 ± 12%		8 ± 6%
Poor risk: MRD	34	1989–1997	47 ± 17%	0.80	53 ± 17%	0.51	9 ± 10%	0.26
Poor risk: MRD	21	1998–2006	46 ± 22%		48 ± 22%		19 ± 17%
Poor risk: URD	22	1989–1997	36 ± 21%	0.11	32 ± 20%	0.67	36 ± 21%	0.17
Poor risk: URD	33	1998–2006	60 ± 17%		27 ± 16%		15 ± 13%

OS, overall survival; RR, relapse risk; TRM, treatment-related mortality; MRD, matched related donor; URD, unrelated donor.

All outcomes are rates at 5 years.

Relapse refers to cumulative incidence of relapse.