Skip to main content
. 2013 Nov 27;306(3):C263–C278. doi: 10.1152/ajpcell.00381.2012

Fig. 13.

Fig. 13.

Effects of inhibitors of phosphatidylinositol 3-kinase, phospholipase C, and protein kinase C on PGE2-induced Isc in mIMCD-K2 cells. A: representative traces show the Isc response to addition of the phosphatidylinositol 3-kinase inhibitor LY294002 (dashed line) (LY, 2.5 × 10−5 M) to both sides or vehicle (solid line) on PGE2-induced Isc in mIMCD-K2 cells. Representative of results obtained from 6 cell sheets. B: representative traces show the Isc response to addition of the phospholipase C inhibitor U73122 (dashed line) (10−6 M) to both sides or vehicle (solid line) on PGE2-induced Isc in mIMCD-K2 cells. Representative of results obtained from 6 cell sheets. C: representative trace shows the Isc response to addition of the PKC inhibitor Go6983 (2 × 10−5 M) to both sides on PGE2-induced Isc in mIMCD-K2 cells. Representative of results obtained from 6 cell sheets.