Table 2.
Hematological values and glucose infusion rate during GSIS studies
| Parameter | Condition | Control | NE | P Value |
|---|---|---|---|---|
| Pre-NE infusion | ||||
| Glucose, mmol/h | Infusion rate | 10.75 ± 1.44 | 10.69 ± 1.12 | NS |
| Glucose, mM | Baseline | 1.19 ± 0.07 | 1.14 ± 0.03 | NS |
| Hyperglycemia | 2.48 ± 0.03 | 2.24 ± 0.03 | <0.05 | |
| Hematocrit, % | Baseline | 34.78 ± 0.82 | 34.00 ± 1.00 | NS |
| Hyperglycemia | 34.73 ± 0.80 | 34.22 ± 0.96 | NS | |
| Po2, mmHg | Baseline | 24.48 ± 0.96 | 24.29 ± 0.83 | NS |
| Hyperglycemia | 23.66 ± 0.99 | 23.75 ± 0.70 | NS | |
| NE, pg/ml | Baseline | 1,262.33 ± 178.76 | 588.89 ± 65.86 | NS |
| Hyperglycemia | 1,434.80 ± 98.11 | 693.23 ± 95.80 | <0.05 | |
| Post-NE infusion | ||||
| Glucose, mmol/h | Infusion rate | 14.79 ± 1.90 | 10.09 ± 1.59 | NS |
| Glucose, mM | Baseline | 0.97 ± 0.05 | 1.15 ± 0.04 | <0.01 |
| Hyperglycemia | 2.38 ± 0.03 | 2.37 ± 0.03 | NS | |
| Hematocrit, % | Baseline | 34.74 ± 0.91 | 30.53 ± 0.87 | <0.01 |
| Hyperglycemia | 35.00 ± 0.84 | 30.68 ± 0.85 | <0.01 | |
| Po2, mmHg | Baseline | 24.57 ± 0.77 | 30.52 ± 0.80 | <0.01 |
| Hyperglycemia | 24.08 ± 0.88 | 32.19 ± 1.06 | <0.01 | |
| NE, pg/ml | Baseline | 903.80 ± 140.37 | 3,189.40 ± 469.70 | <0.01 |
| Hyperglycemia | 1,329.35 ± 181.32 | 3,415.22 ± 392.04 | <0.01 |
Values are means ± SE and represent plasma glucose and NE concentrations, hematocrit, and partial pressure of blood oxygen (Po2) for treatment conditions.
GSIS, glucose-stimulated insulin secretion; NS, not significant.
Differences were determined between treatment groups for pre- and posttreatment GSIS studies.