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Definition of the femoral cancellous and cortical volumes of interest (VOIs) from WT and Scarb1 null mouse bones. The growth plate (GP) reference point is represented by the dashed line; VOI top and bottom are represented by filled lines. The average bone mineral density (BMD) was determined by microCT in 2-mo-old (A) and 4-mo-old (B) individuals. Values are means ± SE from 6–10 mice in each group. *P < 0.05 and **P < 0.01.
