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. 2013 Nov 19;306(1):E48–E57. doi: 10.1152/ajpendo.00421.2013

Fig. 5.

Fig. 5.

In vitro characterization of marrow-derived stromal cells (MSCs) from WT and Scarb1 null male mouse long bones. Marrow was harvested from 2-mo-old mouse femora and tibiae and characterized. A: time course of WT and null MSC proliferation; Bonferroni post hoc test, **P < 0.01 and ***P < 0.001 vs. WT. Inset, no. of adherent MSCs isolated from WT and null bone marrow; Bonferroni post hoc test, ***P < 0.001 vs. WT. B: cellular ALP activity in MSCs grown in osteogenic media for 21 days; paired Student's t-test, *P < 0.05. C: mineralization potential of MSCs grown in osteogenic media for 21 days; paired Student's t-test, **P < 0.01. D: genic expression of osterix (Sp7), collagen 1 alpha 1 (Col1a1), and caveolin-1 (Cav1) in null MSCs relative to WT MSCs; paired Student's t-tests, *P < 0.05 and **P < 0.01. All experiments are from 3–4 independent cell preparations.