Table 3.

Average dynamic histomorphometric values from femora of WT and null mice

	Males		Females
	WT	Null	WT	Null
Relative OB surface, %	20.5 ± 1.5	29.1 ± 3.0**	20.5 ± 2.4	26.9 ± 1.4*
No. of Oc/mm, mm−1	5.2 ± 0.2	4.0 ± 0.3	5.4 ± 0.6	6.9 ± 0.6
Trabecular mineral apposition rate, μm/day	1.48 ± 0.04	1.85 ± 0.06**	1.25 ± 0.20	1.61 ± 0.05*
Cortical mineral apposition rate, μm/day	3.9 ± 0.5	5.3 ± 0.7	3.31 ± 0.76	5.50 ± 1.15*
Percent mineralizing surface, %	23.3 ± 2.3	32.0 ± 2.9*	22.6 ± 1.1	33.6 ± 0.9*
Bone formation rate/bone surface, μm2 · μm−1 · day−1	0.35 ± 0.04	0.59 ± 0.07***	0.28 ± 0.06	0.43 ± 0.03*

Values are means ±SE from 5–7 mice in each group. OB, osteoblasts; Oc, osteoclasts. Bonferroni post hoc test:

^*P < 0.05,

^**P < 0.01, and

^***P < 0.001 vs. corresponding WT.