Table 10.

WAT inflammation-associated gene expression in obese healthy and T2DM women^*

	Healthy Obese	T2DM Obese	P Value
Omental WAT
CD68	100.0 ± 13.7	219.9 ± 47.1	0.02
ITGAX	100.0 ± 20.2	263.9 ± 64.8	0.02
ITGAD	100.0 ± 30.2	126.9 ± 31.4	0.55
TNF	100.0 ± 14.5	232.3 ± 106.9	0.19
IL6	100.0 ± 88.7	62.6 ± 23.0	0.71
IL1B	100.0 ± 31.0	196.7 ± 47.9	0.10
CCL2	100.0 ± 37.5	117.9 ± 35.2	0.74
NOS2	100.0 ± 21.3	146.3 ± 35.3	0.26
THBS1	100.0 ± 21.7	83.8 ± 17.6	0.58
TGFB1	100.0 ± 19.2	177.2 ± 36.5	0.06
ARG2	100.0 ± 29.2	97.2 ± 24.2	0.94
sc WAT
CD68	100.0 ± 15.9	104.4 ± 17.3	0.85
ITGAX	100.0 ± 19.2	122.8 ± 43.3	0.62
ITGAD	100.0 ± 29.7	82.2 ± 34.0	0.71
TNF	100.0 ± 21.6	67.3 ± 15.1	0.24
IL6	100.0 ± 90.5	18.3 ± 5.7	0.41
IL1B	100.0 ± 23.1	71.2 ± 20.9	0.37
CCL2	100.0 ± 22.4	79.2 ± 24.7	0.54
NOS2	100.0 ± 15.3	84.0 ± 22.0	0.55
THBS1	100.0 ± 21.7	41.2 ± 8.3	0.03
TGFB1	100.0 ± 13.7	84.5 ± 16.3	0.47
ARG2	100.0 ± 16.7	57.7 ± 9.2	0.05

Values are presented as means ± SE.

^*mRNA abundances measured in a subset of subjects with available samples, expressed as percent of healthy obese group mean (n = 11 and 9 for omental; n = 9 and 8 for sc WAT in healthy and T2DM, respectively). Values that differ significantly (P < 0.05) or display potential trends (P < 0.1) by Student's t-test are indicated in boldface.