Low-magnification immunohistochemical localization of Rhesus (Rh) glycoproteins, Rh B and Rh C Glycoprotein (Rhbg and Rhcg, respectively), expression in control (C) and floxed Rhbg and Rhcg, Ksp-cadherin-Cre-positive (CD-Rhbg/Rhcg-KO) mice fed a normal diet. A and C: Rhbg and Rhcg immunolabel in C mice kidney. A normal distribution of Rhbg and Rhcg immunolabel in the cortex, outer stripe of outer medullary collecting duct (OSOM), inner stripe of outer medullary collecting duct (ISOM), and inner medulla (IM) is present. B and D: Rhbg and Rhcg immunolabel in CD-Rhbg/Rhcg-KO mice kidney. In CD-Rhbg/Rhcg-KO mice, Rhbg and Rhcg immunoreactivity is only present in the cortex. No Rhbg and Rhcg immunolabel appears in the OSOM, ISOM, and IM.