Fig. 7.

Phosphenolpyruvate carboxykinase (PEPCK) expression in normal and acid-loaded diet C and CD-Rhbg/Rhcg-KO kidneys. A: immunoblot analysis of PEPCK in the cortex and OM of CD-Rhbg/Rhcg-KO and C mice on a normal diet and when acid loaded. B: quantification of PEPCK expression. CD-Rhbg/Rhcg-KO did not alter PEPCK expression in either the cortex or OM in mice on a normal diet. PEPCK expression was significantly greater in acid-loaded CD-Rhbg/Rhcg-KO than in acid-loaded C mice in both the cortex and OM. Values are means ± SE; n = 4/group.